Louise Losos has enjoyed a diverse career in education and leadership for more than 20 years. In addition to her tenure as the principal of Clayton High School, Louise Losos worked as the assistant principal at Parkway West High School from 2000 until 2005. She was responsible for developing discipline policy, administration, and supporting diversity and cultural awareness.

In 2001, the U.S. Congress created the No Child Left Behind (NCLB) Act, which revised and reauthorized the 1965 Elementary and Secondary Education Act. NCLB strives to give students in every American public school access to safe learning environments while supporting vital learning goals and academic achievement. Through these efforts, NCLB aims to close the achievement gap in American schools between children from advantaged backgrounds and those from underserved populations or who have disabilities.

NCLB requires public elementary and high schools to measure their performance progress through a standardized test given to all students within each state. The results are used to assess the adequate yearly progress (AYP) of the school in question, with reform, restructure, and corrective measures made available to schools that perform poorly.